What does it mean if your ALP is high?
ALP is an enzyme found throughout the body, but it is mostly found in the liver, bones, kidneys, and digestive system. When the liver is damaged, ALP may leak into the bloodstream. High levels of ALP can indicate liver disease or bone disorders.
What does ALP mean on a blood test?
Definition. Alkaline phosphatase (ALP) is a protein found in all body tissues. Tissues with higher amounts of ALP include the liver, bile ducts, and bone. A blood test can be done to measure the level of ALP. A related test is the ALP isoenzyme test .
What is normal ALP level?
The normal range is 44 to 147 international units per liter (IU/L) or 0.73 to 2.45 microkatal per liter (µkat/L). Normal values may vary slightly from laboratory to laboratory. They also can vary with age and sex. High levels of ALP are normally seen in children undergoing growth spurts and in pregnant women.
What medications cause high levels of alkaline phosphatase?
Some examples of drugs that may cause a raised alkaline phosphatase include:
- Antibiotics: penicillin derivatives (1)
- Antiepileptic drugs: Carbamazepine.
- Antihistamines: Cetirizine (1)
- Cardiovascular drugs: Captopril (1)
- Disease modifying agents:
- Polycyclic aromatic hydrocarbons:
- Psychotropic drugs:
- Diabetes drugs:
Can low vitamin D cause elevated alkaline phosphatase?
Vitamin D deficiency is reemerging worldwide (5), and elevated serum ALP is a hallmark of this disease (1). Vitamin D deficiency may fail to be diagnosed if serum ALP is not elevated.
How can I lower my ALP?
Some good options include milk thistle, NAC, taurine, B vitamins, and vitamin C. Additionally, get enough sun, exercise, omega-3 fatty acids, and coffee. Reduce alcohol and stop smoking — they both lower alkaline phosphatase levels and support good health.
Should I worry about elevated alkaline phosphatase?
Higher-than-normal levels of ALP in your blood may indicate a health concern with your liver or gallbladder. This could include a blockage in your bile ducts, gallstones, cirrhosis, liver cancer, and some forms of hepatitis.
What cancers cause elevated alkaline phosphatase?
Serum ALP levels are elevated in patients with primary and metastatic tumors of the liver and bone, such as hepatic metastasis of colorectal cancer and bone and liver involvement in breast cancer. [1,4] In patients with malignancies, therefore, an elevated serum ALP may be an indicator of metastatic disease.
What drugs can cause high alkaline phosphatase?
Why is my alkaline phosphatase elevated?
Biliary obstruction, also known as bile duct obstruction, can cause elevated alkaline phosphatase levels. According to the University of Maryland Medical Center, biliary obstruction is a blockage of the tubes that transport bile from your liver to your gallbladder and small intestine.
Why does my doctor test alkaline phosphatase?
This test checks the health of your liver, Alkaline phosphatase is an enzyme that can build up in your blood if your liver doesn’t work right. Doctors often use this test to look for blocked bile ducts.
What is ALKP and Alt in a vet lab test?
Alkaline phosphatase (ALKP): Elevations in this test may indicate liver damage, Cushing’s disease or active bone growth in a young dog; Alanine aminotansferase (ALT): This test may determine active liver damage, but does not indicate the cause; Amylase (AMYL): Elevations in this test indicate pancreatitis or kidney disease
What is Alpi lab test?
The ALP isoenzyme test is a lab test that measures the amounts of different types of ALP in the blood. The ALP test is a related test. A blood sample is needed. Most of the time blood is drawn from a vein located on the inside of the elbow or the back of the hand.