What is the concentration of benzalkonium chloride?
Benzalkonium chloride (BAK) is a preservative used in many ophthalmic medications up to concentrations of 0.01%. It is also used in alcohol-free hand sanitizers at concentrations of 0.1% or higher.
What is benzalkonium chloride 80%?
Product: Benzalkonium Chloride (Alquat -80) (BKC) Applications: It is Quaternary ammonium compound. It is used as biocide in water treatment chemical and as disinfectant also. Used as antibacterial.
Is benzalkonium chloride an antiseptic or disinfectant?
Benzalkonium chloride is widely used as a preservative in eye-drops, in higher concentrations it is used as an antiseptic and disinfectant.
Is .1 benzalkonium chloride safe?
This cosmetic ingredient is not a sensitizer to normal humans at concentrations of 0.1%, but may be to individuals with diseased skin. It is concluded that Benzalkonium Chloride can be safely used as an antimicrobial agent at concentrations up to 0.1%.
Is benzalkonium chloride bactericidal or bacteriostatic?
Benzalkonium chloride solutions are fast-acting biocidal agents with a moderately long duration of action. They are active against bacteria and some viruses, fungi, and protozoa. Bacterial spores are considered to be resistant. Solutions are bacteriostatic or bactericidal according to their concentration.
What is benzalkonium chloride solution?
BENZALKONIUM CHLORIDE (ben zal KOE nee um klor ide) is an antiseptic. It is used prior to surgical procedures or for minor wound care to reduce risks of infection. It may be used for cold sore care. COMMON BRAND NAME(S): Zephiran.
What is the common name for benzalkonium chloride?
Benzalkonium chloride (BZK, BKC, BAK, BAC), also known as alkyldimethylbenzylammonium chloride (ADBAC) and by the trade name Zephiran, is a type of cationic surfactant. It is an organic salt classified as a quaternary ammonium compound.
How long does benzalkonium chloride stay on surfaces?
By nature of being alcohol-free and long-lasting (4-hours on skin, 20+ days on surfaces), the world is now experiencing persistence, purity, and peace of mind with GlanHealth™ sanitizing products. For additional information click here.
Why is benzalkonium chloride harmful?
Clinically, benzalkonium chloride may cause eye irritation and is known to discolour soft contact lenses. Benzalkonium chloride in eye drops has also been reported to cause punctate keratopathy and/or toxic ulcerative keratopathy, especially in frequent or prolonged use or in conditions where the cornea is compromised.
What is benzalkonium chloride 0.1 used for?
Lozenges containing benzalkonium chloride are used for the treatment of superficial infections of the mouth and throat . Benzalkonium chloride is a quaternary ammonium antiseptic and disinfectant with actions and uses similar to those of other cationic surfactants.
How do you make a benzalkonium chloride solution?
Benzalkonium chloride 0.1% is a quaternary ammonium compound that can be made by methylating a primary amine from a fatty acid or a blend of fatty acids to form dimethyl alkylamine. This is then quaternized with benzyl chloride.
Is benzalkonium chloride an antiseptic detergent?
As a cationic detergent in the family of quaternary ammonium compounds, benzalkonium chloride (BZK) shows strong antiseptic activity against both gram-positive and -negative bacteria. In terms of skin sensitization, the irritant action of BZK has been shown to be minimal and more gentle than that of ethanol-based antiseptics 2-4.
How much benzalkonium chloride is in a sanitary wipe?
In a randomized crossover study two concentrations of benzalkonium chloride, 0.1% and 0.4%, used as a sanitary wipe were compared with a 62% ethyl alcohol emollient gel for safety and acceptability in male genital antisepsis (19 c).
What does benzalkonium chloride do to the body?
It is a quaternary ammonium compound that acts as an antimicrobial agent by denaturing proteins and disrupting cytoplasmic membranes. Sensory systems Ocular surface disturbances secondary to the toxic effects of benzalkonium chloride lead to a shift in inflammatory mediators and migration of Langerhans cells.
Does benzalkonium chloride increase histamine sensitivity?
Benzalkonium chloride accentuated the severity of rhinitis medicamentosa and increased histamine sensitivity in a 30-day study with oxymetazoline nasal spray in healthy volunteers [7,8]. Benzalkonium chloride is widely used as a preservative in eye-drops, in higher concentrations it is used as an antiseptic and disinfectant.